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Algorithmic Debugging with RISC.

Published in Journal of Medicinal Chemistry • Jan 1, 1995
Authors:
Gerhard Tobermann
,
Clemens Beckstein

Abstract

Given the putative role of PHGDH in cancer, development of inhibitors is required to explore its function. In this context, we established and validated a straightforward enzymatic assay suitable for high-throughput screening and we identified inhibitors with similar chemical scaffolds. Through a co...

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