TD-1211 Demonstrates Constipation-relieving Effects, Including Decrease in Rescue Laxative Use, in Patients with Opioid-Induced Constipation: 2011 ACG Presidential Poster

Purpose: To investigate the safety, tolerability, and constipation-relieving effects of TD-1211, a potent, peripherally-restricted, neutral, μ-opioid receptor antagonist, in non-cancer pain patients with opioid-induced constipation (OIC). Methods: We conducted an IRB-approved, placebo-controlled, do... View More