Proteasome Inhibitors Decrease AAV2 Capsid-Derived Peptide Epitope Presentation On MHC Class I Following Transduction.
Published in Blood • Nov 20, 2009
NobleIDNI1P61W54R35S04
Authors:,,
Jonathan D. Finn
Daniel J. Hui
Downey Harre
Abstract
Abstract Abstract 695 Adeno-associated viral (AAV) vectors are one of the most extensively studied and highly used vector platforms for gene therapy applications. We have recently provided evidence for AAV capsid-derived antigen presentation through MHC class I on the surface of AAV-transduced cells...
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