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An Optimization Algorithm for Missing Value Imputation in Microarray Based on Integrated Information

Published in Frontiers in artificial intelligence and applications • Jan 1, 2019
Authors:
Feng Liu
,
Yiding Zhang
,
Zeming Liu

Abstract

The technology of DNA microarray enables researchers to obtain thousands of gene expression data simultaneously, but for biological and technical reasons, inevitable missing values exist. We developed an optimization algorithm that preselects imputation candidates based on numerical features and bio...

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