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结直肠无蒂锯齿状腺瘤的筛检及临床处理策略探讨

邱野, 付祥胜, 彭燕

Zhonghua xiaohua neijing zazhi20 Mar 2014

NobleIDark:/48914/w1/20260515/B2E9DCBBDOI10.3760/cma.j.issn.1007-5232.2014.03.022

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Abstract

近年来提出的“锯齿状癌变途径”是一条受到广泛重视的结直肠癌(colorectal callcer,CRC)癌变通路[1]。锯齿状息肉主要包括增生性息肉(hyperplastic polyp,HP)、无蒂锯齿状腺瘤(sessile serrated adenoma,ssA)和传统锯齿状腺瘤(tra—ditional serrated adenoma,TSA)。SSA是新近发现的、具有高危恶变倾向的病变,与右半结肠CRC密切相关[2-3]。SSA的早期检出和正确处理是阻止其进展及癌变的重要途径,但目前尚缺乏统一的诊断标准及处理策略[3]。

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