The aim of the research : To determine the level of effectiveness and justification of stenting of the main pancreatic duct in the modern surgical practice, in order to prevent the development and treatment of acute pancreatitis, in particular, complicated forms of acute pancreatitis, postoperative acute pancreatitis and severe forms of acute pancreatitis. Materials and methods : An analysis of various domestic and foreign medical literary sources that have information and data from their own and third-party research on the treatment and prevention of acute pancreatitis by stenting the main pancreatic duct was made, including articles, monographs, journals and textbooks for students of higher educational institutions and residents. The results of the study : A literature review revealed that the vast majority of sources indicate a positive effect of stenting of the main pancreatic duct on the treatment and prevention of acute pancreatitis, including with severe postoperative course and the presence of complications. However, in some clinical situations, this method requires risk weighing. For instance, stenting in the presence of a significant area of pancreatic necrosis, together with the inexperience of the operating surgeon, can worsen the prognosis of a favorable outcome or lead to even greater complications from the pancreas. Conclusion : The analysis shows that stenting of the main pancreatic duct in the treatment and prevention of various forms and degrees of acute pancreatitis leads to a significant decrease in the incidence and number of deaths, which indicates the high justification and effectiveness of using this method in modern surgical practice. In order to achieve the greatest possible success and prevent immediate and long-term complications, it is necessary to carefully consider all risk factors and analyze each clinical case in detail.