Research indexAnimal study
ПОКАЗАТЕЛИ ТКАНЕВОЙ МИКРОГЕМОДИНАМИКИ КРЫС ПРИ ДЕЙСТВИИ АЦЕТИЛСАЛИЦИЛОВОЙ КИСЛОТЫ И ЕЕ КОМПЛЕКСНЫХ СОЕДИНЕНИЙ С МЕТАЛЛАМИ
Раваева, Чуян, Миронюк and 2 others
Журнал эволюционной биохимии и физиологии1 Jan 2021Open access
NobleIDark:/48914/w1/20260516/BF222C54DOI10.31857/s0044452921010083
ПОКАЗАТЕЛИ ТКАНЕВОЙ МИКРОГЕМОДИНАМИКИ КРЫС ПРИ ДЕЙСТВИИ АЦЕТИЛСАЛИЦИЛОВОЙ КИСЛОТЫ И ЕЕ КОМПЛЕКСНЫХ СОЕДИНЕНИЙ С МЕТАЛЛАМИ
Раваева, Чуян, Миронюк and 2 others · Журнал эволюционной биохимии и физиологии · 2021
NobleIDark:/48914/w1/20260516/BF222C54DOI10.31857/s0044452921010083
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Abstract
The effect of acetylsalicylic acid and acetylsalicylates of (Co2 +), zinc (Zn2 +), nickel (Ni2+) and manganese (Mn2+) at doses of 5 and 10 mg/kg on rat tissue microhemodynamics was studied. It was established that the coordination compounds of metal salicylates demonstrate novel properties and a more pronounced biological effect compared to a parent compound, acetylsalicylic acid. This favors further search for biological and pharmacological activities among newly synthesized coordination compounds of acetylsalicylic acid.