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Array Shape Estimation Using a Hidden Markov Model

Published in International Journal of Molecular Sciences • Jan 1, 1993
Authors:
Barry G. Quinn
,
Ross Barrett
,
Peter J. Kootsookos

Abstract

Ritonavir is the most potent cytochrome P450 (CYP) 3A4 inhibitor in clinical use and is often applied as a booster for drugs with low oral bioavailability due to CYP3A4-mediated biotransformation, as in the treatment of HIV (e.g., lopinavir/ritonavir) and more recently COVID-19 (Paxlovid or nirmatre...

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