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Predicting Function from Sequence♦

Published in Journal of Biological Chemistry • Aug 1, 2006
NobleIDNI8P73W01R89S44

Abstract

Is it possible to predict how changes in sequence will affect the biophysical properties of a protein? In this study, Lucy G. Randles and colleagues attempt to answer this question by using stable, well characterized model proteins to predict the properties of disease-associated proteins in the same...

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