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Published in Clinical Pharmacology & Therapeutics • Nov 1, 2004
NobleIDNI7P34W62R92S16
Authors:
S JOEL
,
Michel Seymour

Abstract

To the Editor: In our study we set out to investigate whether oxaliplatin had an effect on the metabolism of 5-fluorouracil (5-FU), principally via dihydropyrimidine dehydrogenase, and whether this was reflected in altered plasma 5-FU pharmacokinetics.1 We noted in the introduction that the synergis...

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