Basic science
Published in Lara D. Veeken • Apr 20, 2015
NobleIDNI7P824W931R431S833
Authors:,,
Adrian Shields
Simon Vyse
Henning Walczak
Abstract
Background: Our previous work has shown that the rs140490 SNP located at 270 bp of the UBE2L3 promoter region is strongly associated with SLE [P 8.6 10 14 , odds ratio 1.30 (95%CI 1.21, 1.39], and the UBE2L3 risk haplotype drives increased UBE2L3 expression in B cells and monocytes. UBE2L3 is an E2 ...
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