Optimization-Based Decoding of Imaging Spatial Transcriptomics Data
Published in bioRxiv (Cold Spring Harbor Laboratory) • Nov 24, 2022
NobleIDNI9P54W77R55S71
Authors:,,
John Bryan
Loïc Binan
Cai McCann
Abstract
Motivation Imaging Spatial Transcriptomics (iST) techniques characterize gene expression in cells in their native context by imaging barcoded probes for mRNA with single molecule resolution. However, the need to acquire many rounds of high-magnification imaging data limits the throughput and impact ...
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