Pediatric Buccal Epithelial Cell Proportions Decrease Reliably With Age: Considerations for PedBE in Pediatric Research

Abstract Children’s cheek swabs, cellularly heterogeneous samples consisting primarily of buccal epithelial cells (BECs), are widely used in epigenetic association studies of pediatric DNA methylation and biomarker creation, e.g., the Pediatric Buccal Epigenetic (PedBE) clock. Although BEC proportio... View More