Abstract This chapter overviews novel US care systems that focus on helping people with mental health issues take control of and rebuild their lives. The author emphasizes the need for care systems to focus on open communication, shared decision-making, and problem-solving. The chapter underscores how funding for services needs to be a much higher priority in local, state, and federal budgets, but that much can be done using innovative methods that move from a primarily biomedical inpatient approach to a broad biopsychosocial outpatient approach. Using this new approach, clinicians, patients, and their families will find much greater success in reclaiming lives from mental illness. This requires a shift from the prevailing 125-year-old paradigm of hopelessness, changes in clinician training programs, and a fresh start for everyone.