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Complement C2

Published in University of Hertfordshire Research Archive (University of Hertfordshire) • Jan 1, 2013
Authors:
Dinasarapu, Ashok Reddy

Abstract

Complement C2 is a single chain serum glycoprotein (110 kDa), which serves as the catalytic subunit of C3 and C5 convertases in the classical and lectin pathways. During complement activation, C2 is cleaved by classical (C1s) or lectin (MBL-associated serine protease-2; MASP-2) proteases into two fr...

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