Decrease in ATP and AMPK activation in sensitive and resistant cell lines

(789031), Alper Y. Kearney; (789032), You-Hong Fan; (789033), Uma Giri; (789034), Babita Saigal; (147452), Varsha Gandhi; (160316), John V. Heymach; (270090), Amado J. Zurita

doi:10.1371/journal.pone.0135962.g002

Public

Decrease in ATP and AMPK activation in sensitive and resistant cell lines.

Published in Figshare • Dec 3, 2015

NobleIDNI1P28W18R65S17

Authors:

Alper Y. Kearney (789031)

,

You-Hong Fan (789032)

,

Uma Giri (789033)

Abstract

<p><b>a.</b> ATP levels in sensitive and resistant ccRCC cell lines after 6 hours of 40 μM 8-chloroadenosine treatment. ATP levels decreased significantly in all cell lines (CAKI1 p<0.01, ACHN p = 0.02, RCC4 p<0.01, RXF393 p<0.01); however, ATP levels were not significantly different between the sen...

Subject

AMPK

Cell culture

Chemistry

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