Mismatched structure could decrease the loading of passenger strand

(35075), Haoquan Wu; (192730), Hongming Ma; (111422), Chunting Ye; (192735), Danielle Ramirez; (111445), Shuiping Chen; (192738), Jessica Montoya; (35079), Premlata Shankar; (192742), Xiaozhong A. Wang; (35081), N. Manjunath

doi:10.1371/journal.pone.0028580.g004

Public

Mismatched structure could decrease the loading of passenger strand.

Published in Figshare • Dec 2, 2015

Authors:

Haoquan Wu (35075)

,

Hongming Ma (192730)

,

Chunting Ye (111422)

Abstract

<p>The passenger strand functionality was compared between no mismatch (m0, white bars) and mismatched (m1+4+10, black bars) structure by co-transfecting the indicated siRNAs with psiCHECK2 vector harboring the corresponding perfectly complementary passenger strand target sequences. The ratio of Ren...

Subject

Luciferase

Bar (unit)

Structural engineering

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