Primary hepatocyte cultures show a significant decrease in mitochondrial oxygen consumption rate but stable mitochondrial ATP production.

<p>Extracellular flux analysis was used to measure the mitochondrial function of primary hepatocytes cultured for 0 to 48 hours. A) Mitochondrial respiration (OCR levels) after glucose stimulation (10 mM). B) Assessment of ATP-linked respiration following the addition of oligomycin (2 μM). Values ar... View More