Academic performance influences the future educational attainment and income, which, in turn, affect health and quality of life. The current review aimed at examining the association of health-related behaviors and academic performance among university students. The study was carried out as a systematic search of publications in the databases of PubMed and CiNii articles, published from 1999 to 2019. As a comprehensive search, the following keywords were used for the abstract, title, and keyword sections: "academic performance", "academic success", "lifestyle", "health behaviors", "university students", "college students". This review, conducted in the university students, that academic performance is associated with the health-related behaviors considered quality of sleep, physical activity, and the frequency of skipping breakfast. Furthermore, most studies were investigated the cross-sectional relationship between the single factor of health-related behavior and academic performance. This review may give us a better insight into a large variety of multivariate factors involved in academic performance of university students.