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ORNA: Algorithm for read normalization using set multi-cover optimization

Published in Zenodo (CERN European Organization for Nuclear Research) • Oct 7, 2021
NobleIDNI7P27W46R63S37
Authors:
Dilip A Durai
,
Marcel H Schulz

Abstract

The de bruijn graph (DBG) is one of the most commonly used data structures for assembly of sequencing data. Reads from the sequencer are chopped into small words of size k (k-mers) which form the nodes of the DBG. Two nodes are connected by an edge if they have a k-1 overlap. Each edge can be labell...

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