Inhibition of PKCδ causes a decrease in viral replication

(6092747), Brian D. Carey; (2934816), Ivan Akhrymuk; (8551095), Bibha Dahal; (8551098), Chelsea L. Pinkham; (8259813), Nicole Bracci; (8551101), Sarah Finstuen-Magro; (3753646), Shih-Chao Lin; (6817874), Caitlin W. Lehman; (4184077), Kevin J. Sokoloski; (45085), Kylene Kehn-Hall

doi:10.1371/journal.ppat.1008282.g004

Public

Inhibition of PKCδ causes a decrease in viral replication.

Published in Figshare • Mar 9, 2020

NobleIDNI6P663W789R699S146

Authors:

Brian D. Carey (6092747)

,

Ivan Akhrymuk (2934816)

,

Bibha Dahal (8551095)

Abstract

<p>U87MG cells were transfected with 50 nM scramble control or PKCδ siRNAs. Seventy-two hours post-transfection, cells were infected with A) VEEV TC-83 (MOI 0.1) or B) VEEV TrD, EEEV GA97, or WEEV 1930 California (MOI 0.1) and viral supernatants collected at 4, 8, and 16 hpi (panel A) or 16 hpi (pan...

Subject

Virology

Biology

Alphavirus

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