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Transcription network analysis by a sparse binary factor analysis algorithm.

Published in Journal of integrative bioinformatics • Jul 23, 2012
NobleIDNI7P60W11R40S47
Authors:
Shikui Tu
,
Runsheng Chen
,
Lei Xu

Abstract

Transcription factor activities (TFAs), rather than expression levels, control gene expression and provide valuable information for investigating TF-gene regulations. The underlying bimodal or switch-like patterns of TFAs may play important roles in gene regulation. Network Component Analysis (NCA) ...

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