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Supervised Factorization to Associate Spatial Transcriptomics with Complementary Molecular Readouts

Published • Sep 30, 2025
NobleIDNI8P34W26R94S47
Authors:
Awal FB
,
Pautler RG
,
Samee MAH

Abstract

Spatial Transcriptomics enables studying gene expression data within spatial context of tissues. Yet understanding how spatial molecular phenomena influence transcriptional patterns remains a key challenge. We propose a novel supervised Non-negative Matrix Factorization (NMF) framework, where superv...

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