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Decrease of alpha-Hasharon globin in beta-thalassaemia.

Published in British journal of haematology • Aug 1, 1978
Authors:
F Conconi
,
R Alberti
,
G M Mariuzzi

Abstract

In time course experiments performed in subjects carrying haemoglobin Hasharon and beta-thalassaemia the synthesis of alphaA-, alphaHasharon-, beta- and gamma-globin has been determined. The alpha-globin molecules synthesized in excess were found to be removed from the red cell cytoplasm (phenomenon...

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