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Decrease in adrenergic axon sprouting in the senescent rat.

Published in Science (New York, N.Y.) • Nov 17, 1978
Authors:
S W Scheff
,
L S Bernardo
,
C W Cotman

Abstract

When the septal area in young adult rats is denervated by a lesion of the fimbria-fornix, adrenergic fibers proliferate within the denervated area. The same operation performed on aged animals gives rise to a qualitatively similar but quantitatively less pronounced response. This reduction in reacti...

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