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Reversible acute decrease in renal function by NSAIDs in cirrhosis.

Published in The American journal of the medical sciences • Sep 1, 1987
NobleIDNI8P31W43R15S95
Authors:
D C Brater
,
S A Anderson
,
D Brown-Cartwright

Abstract

The effects of sulindac were compared with those of ibuprofen or naproxen on creatinine clearance and urinary prostanoids in patients with severe alcoholic cirrhosis. Sulindac caused acute declines in all renal parameters in four of five patients. The effect occurred with serum concentrations of the...

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