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Acetylcholine esterase and peripherin mRNA level decrease in wobbler mouse.

Published in Neuroreport • Mar 7, 1995
NobleIDNI4P70W81R58S40
Authors:
R Pernas-Alonso
,
A E Schaffner
,
C T Hansen

Abstract

Homozygote wobbler mice develop motoneurone degeneration. Throughout development the expression of choline acetyltransferase, of trkC receptor and F3 adhesion molecule genes is similar in wobbler and wild-type spinal cord. Acetylcholinesterase mRNA level instead is decreased to about 50% with respec...

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