Cardioprotective drugs decrease the Na+ background current.
Published in Yonsei medical journal • Jul 1, 1995
NobleIDNI4P99W06R62S04
Authors:,,
S R Park
G H Ryu
C K Suh
Abstract
Cardiac dysfunctions such as myocardial functional failure and ventricular arrhythmia have been largely attributed to intracellular Ca2+ overload. One of the mechanisms of intracellular Ca2+ overload involves a rapid influx of Ca2+ via Na(+)-Ca2+ exchange during the reperfusion which utilizes the ac...
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