Decrease in left ventricular contractility after tumor necrosis factor-alpha infusion in dogs

Walley, K R; Hebert, P C; Wakai, Y; Wilcox, P G; Road, J D; Cooper, D J

doi:10.1152/jappl.1994.76.3.1060

Public

Decrease in left ventricular contractility after tumor necrosis factor-alpha infusion in dogs.

Published in Journal of applied physiology (Bethesda, Md. : 1985) • Mar 1, 1994

NobleIDNI8P99W78R65S82

Authors:

K R Walley

,

P C Hebert

,

Y Wakai

Abstract

Whether systolic contractility or diastolic compliance changes soon after tumor necrosis factor-alpha (TNF-alpha) exposure is not known. Accordingly, we measured hemodynamics, left ventricular contractility using the slope of the end-systolic pressure-volume relationship, and diastolic pressure-volu...

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