B cell dysfunction after bone marrow transplantation is associated with decreased Ca2+ flux upon membrane Ig crosslinking

Storek, J; Hultin, L E; Ferrara, S; Ku, N; Giorgi, J V; Champlin, R E; Saxon, A

doi:10.1006/clin.1994.1133

Public

B cell dysfunction after bone marrow transplantation is associated with decreased Ca2+ flux upon membrane Ig crosslinking.

Published in Clinical immunology and immunopathology • Aug 1, 1994

NobleIDNI2P20W50R12S75

Authors:

J Storek

,

L E Hultin

,

S Ferrara

Abstract

Patients undergoing bone marrow transplantation have a long-lasting defect of B cell-mediated immunity. Both quantitative (decreased blood B cell counts) and qualitative (decreased Ig production) abnormalities of B cells have been described. To better understand the mechanism of the qualitative defe...

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