Decrease in nosocomial Clostridium difficile-associated diarrhea by restricting clindamycin use

Pear, S M; Williamson, T H; Bettin, K M; Gerding, D N; Galgiani, J N

doi:10.7326/0003-4819-120-4-199402150-00003

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Decrease in nosocomial Clostridium difficile-associated diarrhea by restricting clindamycin use.

Published in Annals of internal medicine • Feb 15, 1994

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Authors:

S M Pear

,

T H Williamson

,

K M Bettin

Abstract

OBJECTIVE: To report the investigation and effective control of a nosocomial epidemic of Clostridium difficile-associated diarrhea. DESIGN: Concurrent surveillance for identification of new nosocomial cases, retrospective case-control analysis, and hospital formulary control of antibiotic use. SETTI...

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