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Endomorphins decrease heart rate and blood pressure possibly by activating vagal afferents in anesthetized rats.

Published in Brain research • Aug 24, 1998
NobleIDNI1P89W47R43S40
Authors:
E H Kwok
,
N J Dun

Abstract

Endomorphin 1 (10, 30, 100 nmol/kg) administered intravenously (i.v. ) to urethane-anesthetized rats consistently and dose-dependently lowered heart rate (HR) and mean arterial pressure (MAP); the decrease in blood pressure recovered faster as compared to the HR. The effects of endomorphin 2 were qu...

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