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Cannabinoids decrease acetylcholine release in the medial-prefrontal cortex and hippocampus, reversal by SR 141716A.

Published in European journal of pharmacology • Aug 21, 1998
NobleIDNI3P02W75R96S78
Authors:
G L Gessa
,
M A Casu
,
G Carta

Abstract

The effect of delta9-tetrahydrocannabinol, the psychoactive principle of marijuana, and [R-(+)-(2,3-dihydro-5-methyl-3-[[4-morpholinylmethyl]pyrol[1,2,3-d e-]-1,4-benzoxazin-6y)(1-naphthalenyl)methanone monomethanesulfonate] (WIN 55,212-2), a synthetic cannabinoid receptor agonist, on the acetylchol...

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