HYDROCORTISONE, ASCORBIC ACID, AND THIAMINE THERAPY DECREASE RENAL OXIDATIVE STRESS AND ACUTE KIDNEY INJURY IN MURINE SEPSIS

J, Kim; A, Stolarski; Q, Zhang; K, Wee; D, Remick

doi:10.1097/shk.0000000000001995

Public

HYDROCORTISONE, ASCORBIC ACID, AND THIAMINE THERAPY DECREASE RENAL OXIDATIVE STRESS AND ACUTE KIDNEY INJURY IN MURINE SEPSIS.

Published in Shock (Augusta, Ga.) • Oct 4, 2022

NobleIDNI9P29W41R81S08

Authors:

Kim J

,

Stolarski A

,

Zhang Q

Abstract

Abstract Background: Acute kidney injury (AKI) occurs frequently in septic patients and correlates with increased mortality. Because clinical studies investigating hydrocortisone, ascorbic acid, and thiamine (HAT) have demonstrated discordant results, studies were performed using mortality stratific...

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