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Electroconvulsive shocks decrease α2-adrenoceptor binding in the Flinders rat model of depression.

Published in European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology • Dec 23, 2014
Authors:
Lillethorup TP
,
Iversen P
,
Fontain J

Abstract

Despite years of drug development, electroconvulsive therapy (ECT) remains the most effective treatment for severe depression. The exact therapeutic mechanism of action of ECT is still unresolved and therefore we tested the hypothesis that the beneficial effect of ECT could in part be the result of ...

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