Relation between paradoxical decrease in high-density lipoprotein cholesterol levels after statin therapy and adverse cardiovascular events in patients with acute myocardial infarction.

T, Ota; H, Ishii; S, Suzuki; A, Tanaka; Y, Shibata; Y, Tatami; S, Harata; Y, Shimbo; Y, Takayama; Y, Kawamura; N, Osugi; K, Maeda; T, Kondo; T, Murohara

doi:10.1016/j.amjcard.2014.11.043

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Relation between paradoxical decrease in high-density lipoprotein cholesterol levels after statin therapy and adverse cardiovascular events in patients with acute myocardial infarction.

Published in The American journal of cardiology • Dec 17, 2014

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Authors:

Ota T

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Ishii H

,

Suzuki S

Abstract

Statin therapy moderately increases high-density lipoprotein cholesterol (HDL-C) levels. Contrary to this expectation, a paradoxical decrease in HDL-C levels after statin therapy is seen in some patients. We evaluated 724 patients who newly started treatment with statins after acute myocardial infar...

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