TNF-alpha induces a decrease in eNOS promoter activity.
Published in American journal of physiology. Lung cellular and molecular physiology • Feb 1, 2004
NobleIDNI6P40W05R04S43
Authors:,,
Paul Neumann
Nancy Gertzberg
Arnold Johnson
Abstract
We determined whether TNF-alpha induces a decrease in activity of the promoter for the endothelial nitric oxide synthase (eNOS) gene in pulmonary microvessel endothelial monolayers (PMEM). eNOS promoter activity was assessed in PMEM transfected with plasmids coding the wild-type (F1: -1600 nt from t...
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