Infectious and inflammatory stimuli decrease endothelial nitric oxide synthase activity in vitro

Cardaropoli, Simona; Silvagno, Francesca; Morra, Emanuella; Pescarmona, Gian Piero; Todros, Tullia

doi:10.1097/00004872-200311000-00020

Public

Infectious and inflammatory stimuli decrease endothelial nitric oxide synthase activity in vitro.

Published in Journal of hypertension • Nov 1, 2003

NobleIDNI2P60W89R32S83

Authors:

Simona Cardaropoli

,

Francesca Silvagno

,

Emanuella Morra

Abstract

BACKGROUND: Perturbation of iron metabolism, especially the increase of serum ferritin levels, is often associated with both inflammation and hypertension. Changes in iron availability can affect an important regulator of vascular tone, the endothelial nitric oxide synthase (eNOS), activated by a he...

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