Modeling microarray data using a threshold mixture model.
Published in Biometrics • Jun 1, 2004
Authors:,
Göran Kauermann
Paul Eilers
Abstract
An important goal of microarray studies is the detection of genes that show significant changes in expression when two classes of biological samples are being compared. We present an ANOVA-style mixed model with parameters for array normalization, overall level of gene expression, and change of expr...
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