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Vector system
KINGSMAN ALAN JOHN, MAZARAKIS NICHOLAS D, MARTIN-RENDON ENCA and 2 others
7 Apr 2003
From the research index
Vector system
KINGSMAN ALAN JOHN, MAZARAKIS NICHOLAS D, MARTIN-RENDON ENCA and 2 others · 7 Apr 2003
Abstract
Provided are retroviral vector genomes and vector systems comprising the genomes. In particular, a retroviral vector genome comprising two or more NOIs, operably linked by one or more Internal Ribosome Entry Site(s); a lentiviral vector genome comprising two or more NOIs suitable for treating a neurodegenerative disorder; and a lentiviral vector genome which encodes tyrosine hydroxylase, GTP-cyclohydrolase I and, optionally, Aromatic Amino Acid Dopa Decarboxylase are provided.
Discussion
Details
- Authors
- KINGSMAN ALAN JOHN, MAZARAKIS NICHOLAS D, MARTIN-RENDON ENCA, AZZOUZ MIMOUN, ROHLL JONATHAN
- Published
- 7 Apr 2003