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Pattern-constrained multiple polypeptide sequence alignment.

Published in Computational biology and chemistry • Aug 1, 2005
NobleIDNI5P64W21R61S99
Authors:
Zhihua Du
,
Feng Lin

Abstract

Multiple sequence alignment (MSA) is one of the fundamental research topics in computational biology. The alignments help us to find functional assignment, evolutionary history and conserved region. Previous methods use a substitution matrix and do not incorporate knowledge of the sequences being al...

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