MODIFIED COMPLEMENT SYSTEM REGULATORS
Published • Apr 7, 2000
Authors:,,
ATKINSON John P.
KRYCH Malgorzata
HAUHART Richard
Abstract
Two functionally distinct but homologous sites in complement receptor type 1 (CR1)(CD35) were characterized by homologous substitution mutagenesis of two CR1 derivatives, each containing one site. In both sites, reducing negative and/or increasing positive charge augmented interaction with iC3/C3b a...
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