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L-methamphetamine and selective MAO inhibitors decrease morphine-reinforced and non-reinforced behavior in rats; Insights towards selegiline's mechanism of action.

Published in Pharmacology, biochemistry, and behavior • Dec 1, 2006
NobleIDNI4P56W11R73S20
Authors:
Shuangteng He
,
Kenneth Grasing

Abstract

Selegiline is an inhibitor of type B monoamine oxidase (MAO) with psychostimulant effects that can decrease morphine-reinforced and non-reinforced responding. The present study was undertaken to compare the effects of MAO inhibition and treatment with L-methamphetamine, the major psychostimulant met...

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