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Full-length hdmX transcripts decrease following genotoxic stress.

Published in Oncogene • Nov 6, 2008
Authors:
M Markey
,
S J Berberich

Abstract

Previous studies have suggested that the mdmX gene is constitutively transcribed, and that MdmX protein activity is instead controlled by cellular localization and DNA damage induced Mdm2-mediated ubiquitination leading to proteasomal degradation. In these studies, we report that the human mdmX (hdm...

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