MULTI-LAYERED CONTROLLED RELEASE FORMULATION
Published • May 20, 1992
Authors:,,
NODA Kazuo
YOSHINO Hiroyuki
HIRAKAWA Yoshiyuki
Abstract
Controlled release pharmaceutical beads are provided having a multi-layered core and a multi-layered periphery. The core contains at least (A) an inner portion having a suitable organic acid and (B) a sustainably-acid-releasing coating thereover. The periphery contains at least (A) an inner portion ...
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