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Can pharmacologic gradient reduction decrease mortality in hypertrophic cardiomyopathy?

Published in Progress in cardiovascular diseases • 2026
NobleIDNI0P02W40R49S76
Authors:
Dan Musat
,
Silviana Marineci
,
Mark V Sherrid

Abstract

Pharmacologic therapy is the first line approach to relieve symptoms in obstructive hypertrophic cardiomyopathy. There are no randomized trials to evaluate their effect on prognosis. Gradient reduction by surgical septal myectomy is associated with excellent prognosis, but not all patients have symp...

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