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Complement inhibition can decrease the haemostatic response in a microvascular bleeding model at multiple levels

Published in Frontiers in Immunology • Sep 13, 2023
Authors:
Murielle Golomingi
,
Jessie Kohler
,
Christina Lamers

Abstract

Background Haemostasis is a crucial process by which the body stops bleeding. It is achieved by the formation of a platelet plug, which is strengthened by formation of a fibrin mesh mediated by the coagulation cascade. In proinflammatory and prothrombotic conditions, multiple interactions of the com...

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