Age-dependent decrease in desflurane concentration for maintaining bispectral index below 50.

BACKGROUND: We examined the hypothesis that the minimum alveolar concentration of desflurane for maintaining bispectral index (BIS) below 50 (MACBIS 50 ) decreases with advance of age. METHODS: Sixty young (20-30 year), middle-aged (31-65 year) and elderly (66-80 year) patients were included (n = 20... View More