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Optimizing frequency sampling in CEST experiments.

Published in Journal of biomolecular NMR • Dec 1, 2022
NobleIDNI9P37W18R22S87
Authors:
Nicolas Bolik-Coulon
,
D Flemming Hansen
,
Lewis E Kay

Abstract

For the past decade chemical exchange saturation transfer (CEST) experiments have been successfully applied to study exchange processes in biomolecules involving sparsely populated, transiently formed conformers. Initial implementations focused on extensive sampling of the CEST frequency domain, req...

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