Fractal Geometry‐Based Decrease in Trimethoprim‐Sulfamethoxazole Concentrations in Overweight and Obese People
Published in CPT: Pharmacometrics & Systems Pharmacology • Nov 21, 2016
NobleIDNI6P40W28R32S01
Authors:,,
RG Hall
JG Pasipanodya
C Meek
Abstract
Trimethoprim‐sulfamethoxazole (TMP‐SMX) is one of the most widely drugs on earth. The World Health Organization recommends it as an essential basic drug for all healthcare systems. Dosing is inconsistently based on weight, assuming linear relationships. Given that obesity is now a global “pandemic” ...
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